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Перевод: atherosclerosis

[существительное]
атеросклероз

Тезаурус:

1. However, the margarine adverts having got to me, and the latest atherosclerosis story beginning to look as though it might be true, I succumbed to the temptation of having my lipids (blood fats, including cholesterol) done.
2. Atherosclerosis appears to proceed at a more rapid rate and is more extensive in the diabetic (Crall Roberts, 1978), but the process does not differ in its morphological appearance nor in its anatomical distribution compared to the non-diabetic (Strandness et al, 1964; Robertson Strong, 1968).
3. It is now well established that diabetics are prone to early atherosclerosis (Epstein et al, 1965 Pirart, 1978; Kannel McGee, 1979) which appears no different from that in non-diabetics (Robertson Strong, 1968).
4. As early as 1907 it was reported that there was a frequent association between hyperglycaemia, hypertension, atherosclerosis and obesity (Elliott, 1907).
5. Although microvascular disease is the specific lesion usually associated with diabetes mellitus, atherosclerosis, particularly of the coronary vessels, accounts for the major morbidity and mortality in diabetic patients.
6. The pathognomonic lesion of atherosclerosis is the fibrous plaque which is probably due to proliferation of the smooth muscle cell in the arterial wall following an initial breach in the arterial intima (Ross Glomset, 1976; Ross Marker, 1976).
7. Likewise, other conditions, such as renal artery stenosis secondary to atherosclerosis, which might be expected to occur more frequently in the diabetic, appear not to do so (Munichoodappa et al, 1979).
8. Epidemiological studies, mainly in the non-diabetic, have demonstrated that hypertension is one of several major risk factors for atherosclerosis (Keys, 1975; Miller et al, 1981).
9. A description will now be given of the aetiological theories and relationships that lipids and lipoprotein levels may have with atherosclerosis.
10. Premature atherosclerosis
11. High cholesterol levels are associated with atherosclerosis, or "furring" of the arteries with fatty deposits, which can lead to a heart attack.
12. Several pathophysiological mechanisms have been implicated including premature atherosclerosis, increased circulating blood volume, a role for insulin, body sodium and catecholamines, abnormal central blood-pressure regulation and abnormalities of function or structure of plasma renin which will now be reviewed.
13. The suggestion that LDL may be having a primary effect is supported by the finding of premature atherosclerosis in the presence of most primary hyperlipidaemia, in particular familial hypercholesterolaemia, in which elevated LDL levels are characteristically found.