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Перевод: metastasis

[существительное]
метастаз

Тезаурус:

1. Assessment of the extent of such mutation in a given tumour may permit assessment of prognosis or predict whether distant metastasis has already occurred.
2. A case of perfectly normal metastasis.
3. It is involved in numerous cellular functions including adhesion, migration and differentiation, angiogenesis, wound healing, embryonic development and tumor cell metastasis (6, and reviewed in 3,4).
4. Some patients with metastasis of unknown origin do have responsive tumours.
5. Secondly, much of the evidence presented in the editorial (and this letter) is based on hypotheses derived from models of invasion and metastasis that may bear little relation to the function of metalloproteinases in vivo.
6. It is also essential for metastasis.
7. In conclusion our results show the potential value of immunoreactivity of tumour markers in assisting identification of the site of the primary tumour in patients with metastasis of unknown origin.
8. The cases used in this study were selected to include a range of primary sites and were not true cases of metastasis of unknown origin.
9. The slow rate of progression to metastasis coupled with the predictable behaviour of localised prostatic cancer provides a window in which the diagnosis can be made before the disease has spread, with a possible reduction in the morbidity and mortality.
10. Metastasis of unknown origin is defined as a metastatic tumour, the primary tumour of which remains occult despite taking a clinical history, physical examination, chest radiography, analysis of blood and urine samples, and histological and electron microscopic evaluation.
11. These peptides are much more potent inhibitors of 1 and 3 integrins than synthetic peptides and inhibit tumour metastasis in mice, as well as platelet aggregation.
12. Gastric carcinoma is very common in patients presenting with metastasis of unknown origin, although at present the antibody's clinical usefulness is questionable as the disease has a poor prognosis.
13. Patients presenting with metastasis of unknown origin have a mean life expectancy of only four months so most diagnostic methods occupy a large proportion of the patient's remaining life and identification of the primary site only rarely influences the choice of treatment.