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Перевод: phosphatase

фосфатаза

Тезаурус:

1. In other cases, treatment with non-ionic detergents, phosphatase or DTT interferes with the interaction of DNA binding proteins with their cognate modulating factors.
2. Though no good new assays exist to supplement assays of alkaline phosphatase to assess bone formation, more specific markers are becoming available for bone resorption.
3. The complexes, except for control reactions, were subsequently treated with 0.2 units alkaline phosphatase during 15 min at 37C and the reactions stopped by the addition of EDTA to 10 mM.
4. The median serum alkaline phosphatase concentration in the women taking tamoxifen was 60.0 (interquartile range 53-;68) U/l compared with 86.5 (68-;110) U/l in the controls (p0.005).
5. He says that, "DTX-2, like its biogenetic relatives acts as an "on-off" switch for certain phosphatase enzymes and could open a door in the cell for us to look inside and see what is going on".
6. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
7. Nuclear extracts from Hep3B cells (either untreated or stimulated with 1000U/ml IL-6) were prepared essentially as described (34) except that the buffers contained the phosphatase inhibitors, sodium fluoride (50mM) and sodium pyrophosphate (10mM).
8. The significantly lower median serum alkaline phosphatase concentration in the women treated with tamoxifen is consistent with an oestrogenic effect of the drug since none of the women had demonstrable hepatic or skeletal metastases at the time of bone biopsy.
9. Calcium stimulates the calmodulin-dependent protein phosphatase calcineurin, which is one of the targets for the immunosuppressant drugs cyclosporin A (Fig. 5) and FK-506 (ref. 132).
10. The cyclosporin A/cyclophilin complex inhibits the calcium- and calmodulin-dependent phosphatase, calcineurin, resulting in a failure to activate genes encoding interleukin-2 and other lymphokines.
11. The cDNA contains an open reading frame specifying a protein of M r 39.3K with the structural features of a non-receptor-type protein-tyrosine phosphatase and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus.
12. b , The CL100 protein has intrinsic phosphatase activity.
13. Zinc ions also strongly repress the CL100 phosphatase.