t ta tb tc td te tg th ti tk tl tm tn to tp tr ts tt tu tv tw tx ty tz

Перевод: tubercle

[существительное]
клубенек [бот.] ; узел [анат.] ; узелок ; бугорок [анат.] ; выступ кости; туберкул

Тезаурус:

1. After the tubercle bacillus was identified, accurate diagnosis of tuberculosis, of the lungs and of other organs, became possible.
2. It is also more toxic, and from an early stage a further disadvantage gradually became apparent: tubercle bacilli become resistant to it remarkably quickly.
3. In Duke University, in North Carolina, F. Bernheim studied the effect of various substances on tubercle bacilli.
4. So the tubercle bacillus is a particularly difficult target for chemical attack.
5. He had slight success with tri-iodobenzoic acid, but it was J. Lehmann, in Sweden, who found that, among some fifty or so compounds tested, p -aminosalicylic acid, commonly known as PAS, prevented the growth of tubercle bacilli.
6. Tissues respond to the presence of tubercle bacilli by forming a fibrous wall round the organisms and encasing them in the small nodules called tubercles.
7. In 1942 his son, then a medical student, urged Waksman senior to isolate strains of Actinomyces active against human tubercle bacilli, but he replied that the time had not come yet.
8. Bernheim's results suggested that he had found some substances which were good for tubercle bacilli, and, by applying the principle of competitive antagonism, he sought closely related compounds which would also be taken up by them but would block the pathway of the stimulants.
9. Furthermore, immune responses to tubercle bacilli are extraordinarily complicated.
10. Tubercle bacilli are included in this table, in a single line, without information about the strain used and whether it was virulent or not.
11. Waksman is said to have been shown a culture of tubercle bacilli which had been killed by a fungus in 1932, but he was not tempted to pursue the implications of this observation.
12. From such work and from studies on the biochemistry of tubercle bacilli, on substances which prevented their growth, and on potential therapeutic agents, extensive research, especially in the USA, led to the substance named isoniazid which was discovered almost simultaneously in the laboratories of E. R. Squibb and of Hoffmann-La Roche and publicized in 1952.
13. As leprosy and tuberculosis are caused by related organisms, nicotinamide was tested against tubercle bacilli.