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Перевод: actin

актин

Тезаурус:

1. Actin cables and epidermal movement in embryonic wound healing
2. They resemble actin filaments found in other contractile cells such as muscle, and platelet actin has a 100-fold excess over platelet myosin (Pollard, 1975).
3. As seen in optical section, it has typically about five times the actin content of an ordinary band of cortical actin (Fig. 4i).
4. The myosin filaments would interdigitate between the actin filaments in opposite directions and help to push the platelet granules into the centre of the platelet for release into the surface-connected open canalicular system.
5. Although the cable has by this stage disappeared, the cells in the mound still contain a great deal of filamentous actin in a disorganized arrangement (Fig. 4 h).
6. We find that a thick band, or cable, of actin runs around almost all of the epidermal wound margin (Fig. 4).
7. Here we show that a cable of filamentous actin appears to run continuously around most of the wound margin.
8. Such contractile machinery would be expected to involve actin.
9. We suggest that the actin cable acts as a contractile "purse string" to close up the embryonic wound.
10. The red blood cell can carry oxygen because it contains the protein haemoglobin, muscles can contract because of the proteins, actin and myosin.
11. Cohen et al (1980) have postulated that the actin filaments are anchored to the platelet membrane by -actin (glycoprotein III), a transmembrane protein.
12. In some regions, the cable is split into several parallel strands, and at a few points around the margin (typically two or three) the continuity of the cable is broken, the actin distribution appears disorderly, and the wound front is irregular rather than smoothly curved; some of these discontinuities may represent sites of stronger attachment to the substratum.