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Перевод: antimalarial

[прилагательное]
противомалярийный

Тезаурус:

1. Perhaps the best known of all recent antimalarial drugs is chloroquine.
2. The support of a British parasitologist Warrington Yorke (1883-;1943), at the Liverpool Institute of Tropical Medicine, who foresaw the wartime problems well in advance, was most important to a programme of research into antimalarial drugs developed at the Imperial Chemical Industries Research Laboratories at Manchester.
3. The information very properly reached the files of the survey for antimalarial compounds under the Survey Number SN-183 and was available to various conferences, committees, and subcommittees on the Co-ordination of Malarial Studies.
4. A sequence of antimalarial drugs of increasing power were produced, culminating in the drug "Paludrine", alias proguanil or chloroguanide, which became publicly known in 1945.
5. Unexpectedly, when sulphanilamide was tried in bird malaria (see Chapter 8), at that time the standard procedure for discovering new antimalarial agents, it did not work.
6. Since this time much progress has been made in understanding the biology of plasmodia and new antimalarial drugs have been discovered.
7. As antimalarial drugs were desperately needed during the war, it is startling to realize that chloroquine was first synthesized several years before the war and recognized at that time as having antimalarial activity.
8. The overall search for new antimalarial agents involved the screening of some 16,000 compounds, most of them for both suppressive and prophylactic activity against several avian malarias, plus a thorough study of the toxicology and pharmacology of many of the preparations in lower animals.
9. In the USA, the need for research into antimalarial drugs had naturally been foreseen.
10. Chemically, the antimalarial drug Atebrin or mepacrine had some resemblance to riboflavin.
11. Much of the work centred on the complex biology of the malaria parasite and on improvements in the methods of testing potential antimalarial drugs.
12. A program on the synthesis of new antimalarial drugs was initiated at the National Institutes of Health in 1939 and formed the basis of a war program organized by the Committee on Medical Research of the Office of Scientific Research and Development, National Research Council.